Letter to the editor: Comparing pace and speed in the pulmonary circulation?

نویسندگان

  • Jonathan R Weir-McCall
  • Allan D Struthers
  • Brian J Lipworth
  • J Graeme Houston
چکیده

TO THE EDITOR: In the American Journal of Physiology-Heart and Circulatory Physiology, we read with interest the article by Quail et al. (2) on the use of noninvasive wave intensity analysis using cardiac MRI for the assessment of pulmonary hypertension. In the article the authors argue their pulse wave velocity (PWV) measurement is accurate and free from reflection, as it closely correlated with a previously described technique by Davies et al. (1) derived from invasive coronary artery catheterization, which accounts for and ameliorates the effects of wave reflections on calculated PWV. The authors use commonly accepted substitutions of flow (Q) for velocity (U) and vessel cross sectional area (A) for pressure (P) as described by other groups (3) to convert the original equation by Davies et al. from Eq. 1 to Eq. 2.

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Reply to: "Letter to the editor: Comparing pace and speed in the pulmonary circulation?".

which does result in wave speed in m/s. However, the correct equation was used in processing of the data in the article (Fig. 1A). In fact, if we had calculated “pace,” a significant bias would be seen, as shown in Fig. 1B. Weir-McCall rightly draws attention to the difficulty of measuring pulse wave velocity (PWV) in the pulmonary circulation and the relatively wide limits of agreement between...

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عنوان ژورنال:
  • American journal of physiology. Heart and circulatory physiology

دوره 310 7  شماره 

صفحات  -

تاریخ انتشار 2016